A serine protease inhibitor. Please enquire for pricing.

A serine protease inhibitor. Please enquire for pricing.

Specific recombinant peptide Thrombin inhibitor

A synthetic specific Thrombin inhibitor.

The benzamidine moiety is a key structure for the development of inhibitors of trypsin-like enzymes. It mimics the protonated side-chain of the basic amino acids Arg and Lys which is hydrolysed by these enzymes. Pefabloc TH (a-NAPAP) is one of the most potent and selective competitive inhibitors of thrombin.

Pefabloc TH can be used in diagnostic systems, analytical applications, research and industrial purification processes to exclude undesired thrombin activity. It can also be used as a potent anticoagulant in in vitro test systems.

Pefabloc SC is an irreversible proteinase inhibitor with broad specificity for serine proteinases.

Pefablocm SC is suitable for biopharmaceutical downstream purification because of its superior solubility, stability, inhibitory activity and low toxicity.

Binds with a high affinity to fibrinogen, inhibits fibrin polymerization, modifies the mechanical properties of fibrin clots and can dissociate non-stabilized fibrin gels.

Pefabloc FG can be added to fibrinogen containing reaction mixtures to inhibit disturbing fibrin-related turbidity, gel formation and fibrin deposition in diagnostic and preparative procedures (e. g. measurement of thrombin generation in plasma). Pefabloc FG can also be used to inhibit fibrin formation during purification and processing of clotting factors and other plasma proteins.

Packsize contains - 3 x 50 mg vials